FAM118A

Across TCGA patient cohorts, FAM118A protein abundance is significantly associated with the RNA expression of many other genes, with 11,621 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM118A-associated genes across cancer lineages are IGHGP, RASL11A, and SPRR1A. Each is linked with FAM118A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM118A-to-partner and partner-to-FAM118A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM118A versus IGHGP in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118A→partner) and Y-score (partner→FAM118A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IGHGP →	+2.967	+0.401	<.001	<.001	3	3
OV	RASL11A →	+1.252	+1.055	.001	<.001	3	2
UCEC	SPRR1A →	-1.740	-0.319	.003	.001	3	2
COAD	IL17D →	+0.519	+0.607	.007	<.001	3	2
HNSC	LINC00885 →	+0.908	+0.378	.002	<.001	3	2
PDAC	RGMA →	+0.251	+0.307	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,621 associations by consensus.

FAM118A vs IGHGP — BRCA

Explore this scatter interactively →