FAM118A

Across TCGA patient cohorts, FAM118A mutation is significantly associated with the RNA expression of many other genes, with 314 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM118A-associated genes across cancer lineages are FAM74A1, BMI1P1, and OR51A3P. Each is linked with FAM118A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM118A-to-partner and partner-to-FAM118A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM74A1 grouped by FAM118A-low versus FAM118A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118A→partner) and Y-score (partner→FAM118A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM74A1 →	+0.069	+7.930	<.001	.008	3	2
BLCA	BMI1P1 →	+0.058	+6.618	<.001	.001	3	2
HNSC	OR51A3P →	+0.034	+4.822	.001	.006	3	2
BLCA	RNU6-1318P →	+0.438	+5.588	<.001	.004	3	2
STAD	MIR7975 →	+0.665	+4.184	.005	.009	3	2
COAD	REG1CP →	+0.261	+3.007	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 314 associations by consensus.

FAM74A1 by FAM118A expression — LUAD

Explore this box plot interactively →