FAM118A

Across TCGA cell cohorts, FAM118A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,177 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM118A-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Negative regulation of chromosome condensation, and Positive regulation of cell fate commitment. Each is linked with FAM118A in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM118A-to-partner and partner-to-FAM118A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T-helper 17 cell lineage commitment grouped by FAM118A-low versus FAM118A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118A→partner) and Y-score (partner→FAM118A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.241	+1.158	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of chromosome condensation →	+0.179	+1.412	<.001	<.001	3	12
STOMACH	Positive regulation of cell fate commitment →	+0.165	+0.808	<.001	<.001	3	10
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.148	+1.108	<.001	<.001	3	10
STOMACH	Positive regulation of mitochondrial fusion →	+0.106	+0.862	.002	.002	3	10
BONE	Regulation of DNA repair →	+0.093	+1.702	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,177 associations by consensus.

Positive regulation of T-helper 17 cell lineage commitment by FAM118A expression — STOMACH

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