FAM117B

Across TCGA patient cohorts, FAM117B protein abundance is significantly associated with the RNA expression of many other genes, with 15,118 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM117B-associated genes across cancer lineages are SPAST, FAM171A2, and SNX16. Each is linked with FAM117B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM117B-to-partner and partner-to-FAM117B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM117B versus SPAST in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM117B→partner) and Y-score (partner→FAM117B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAST →	+0.731	+0.472	<.001	<.001	3	4
OV	FAM171A2 →	+1.385	+0.754	<.001	<.001	3	4
LSCC	SNX16 →	+0.533	+0.515	.001	<.001	3	3
OV	BCL7A →	+0.697	+0.743	<.001	<.001	3	3
OV	RSRC2 →	+0.324	+0.499	.005	.005	3	3
LSCC	CACYBP →	+0.463	+0.381	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,118 associations by consensus.

FAM117B vs SPAST — LSCC

Explore this scatter interactively →