FAM117B

Across TCGA cell cohorts, FAM117B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,295 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM117B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Urokinase plasminogen activator signaling pathway, and Host-mediated perturbation of viral transcription. Each is linked with FAM117B in more than 14 cancer types. Because this analysis shows association rather than direction, both FAM117B-to-partner and partner-to-FAM117B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by FAM117B-low versus FAM117B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM117B→partner) and Y-score (partner→FAM117B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA repair →	+0.084	+0.866	<.001	<.001	3	15
LIVER	Urokinase plasminogen activator signaling pathway →	-1.402	-0.855	.001	<.001	3	13
SOFT_TISSUE	Host-mediated perturbation of viral transcription →	+0.093	+0.726	.001	.001	3	13
STOMACH	Host-mediated activation of viral transcription →	+0.099	+0.827	.001	.004	3	13
LUNG_SCLC	Positive regulation of calcium ion transport into cytosol →	-0.338	-0.691	.002	<.001	3	13
SOFT_TISSUE	External encapsulating structure organization →	-0.172	-0.766	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,295 associations by consensus.

Positive regulation of DNA repair by FAM117B expression — SOFT_TISSUE

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