FAM114A2

Across TCGA cell cohorts, FAM114A2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAM114A2-associated genes across cancer lineages are R3HDML, CABP5, and BANF2. Each is linked with FAM114A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM114A2-to-partner and partner-to-FAM114A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R3HDML grouped by FAM114A2-low versus FAM114A2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM114A2→partner) and Y-score (partner→FAM114A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	BANF2 →	+0.047	+5.643	<.001	.002	3	1
LARGE_INTESTINE	RFPL3 →	+0.058	+4.095	<.001	.009	3	1
LARGE_INTESTINE	FCGR3B →	+0.174	+4.467	<.001	.004	3	1
LARGE_INTESTINE	KRTAP10-1 →	+0.009	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

R3HDML by FAM114A2 expression — BLOOD_Lymphoma

Explore this box plot interactively →