Across TCGA patient cohorts, FAM114A1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,125 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM114A1-associated genes across cancer lineages are SRPX2, SEC24D, and CTHRC1. Each is linked with FAM114A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM114A1-to-partner and partner-to-FAM114A1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM114A1→partner) and Y-score (partner→FAM114A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRPX2 →	+1.289	+0.407	<.001	<.001	3	9
OV	SEC24D →	+0.721	+0.387	<.001	<.001	3	9
OV	CTHRC1 →	+1.782	+0.442	<.001	<.001	3	8
OV	MSRB3 →	+1.091	+0.405	<.001	<.001	3	8
OV	KDELR3 →	+0.964	+0.398	<.001	<.001	3	8
GBM	GPX8 →	+1.163	+0.491	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,125 associations by consensus.

Exploration

FAM114A1 survival (RNA) · tumor vs normal (RNA) · all FAM114A1 data types