Across TCGA patient cohorts, FAM114A1 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM114A1-associated genes across cancer lineages are EGFR_pY1068, ERK2, and FoxM1. Each is linked with FAM114A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM114A1-to-partner and partner-to-FAM114A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM114A1→partner) and Y-score (partner→FAM114A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.321	-3.700	.001	.001	3	1
UCEC	ERK2 →	+0.167	+2.999	.031	.035	3	1
UCEC	FoxM1 →	+0.230	+2.415	.027	.003	3	1
UCEC	GATA6 →	-0.136	-2.321	.037	.034	3	1
UCEC	Heregulin →	-0.138	-1.700	.005	.042	3	1
UCEC	INPP4B →	-0.323	-3.459	.012	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

FAM114A1 survival (RNA) · tumor vs normal (RNA) · all FAM114A1 data types