Across TCGA cell cohorts, FAM114A1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM114A1-associated genes across cancer lineages are H2BW2, BTN1A1, and RIT2. Each is linked with FAM114A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM114A1-to-partner and partner-to-FAM114A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM114A1→partner) and Y-score (partner→FAM114A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	H2BW2 →	+0.092	+4.467	<.001	.004	3	1
SKIN	BTN1A1 →	+0.216	+4.095	<.001	.009	3	1
SKIN	RIT2 →	+0.030	+5.022	<.001	.002	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	TNMD →	+0.168	+4.684	<.001	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.042	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

FAM114A1 survival (RNA) · tumor vs normal (RNA) · all FAM114A1 data types