Across TCGA patient cohorts, FAM111B protein abundance is significantly associated with the RNA expression of many other genes, with 9,302 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM111B-associated genes across cancer lineages are GINS1, MYBL2, and E2F1. Each is linked with FAM111B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM111B-to-partner and partner-to-FAM111B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111B→partner) and Y-score (partner→FAM111B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GINS1 →	+1.387	+1.203	.002	<.001	3	6
UCEC	MYBL2 →	+1.467	+0.702	<.001	.002	3	6
PDAC	E2F1 →	+1.282	+1.154	<.001	.001	3	6
PDAC	MCM4 →	+1.342	+1.269	<.001	<.001	3	6
UCEC	NCAPG →	+1.330	+0.914	<.001	<.001	3	6
UCEC	FBXO5 →	+0.977	+0.886	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,302 associations by consensus.

Exploration

FAM111B survival (RNA) · tumor vs normal (RNA) · all FAM111B data types