FAM111B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM111B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,650 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM111B-associated GO terms across cancer lineages are Protein-DNA covalent cross-linking repair, Positive regulation of chromosome segregation, and Regulation of mitotic nuclear division. Each is linked with FAM111B in more than 18 cancer types. Because this analysis shows association rather than direction, both FAM111B-to-partner and partner-to-FAM111B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111B→partner) and Y-score (partner→FAM111B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEProtein-DNA covalent cross-linking repair →+0.116+1.783<.001<.001319
SOFT_TISSUEPositive regulation of chromosome segregation →+0.154+1.682<.001<.001318
UPPER_AERODIGESTIVE_TRACTRegulation of mitotic nuclear division →+0.145+1.712<.001<.001317
SOFT_TISSUENegative regulation of cell cycle phase transition →+0.056+1.619<.001<.001317
UPPER_AERODIGESTIVE_TRACTNegative regulation of metaphase/anaphase transition of cell cycle →+0.195+1.888<.001<.001317
UPPER_AERODIGESTIVE_TRACTNegative regulation of chromosome separation →+0.195+1.888<.001<.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,650 associations by consensus.

Exploration