Across TCGA cell cohorts, FAM111B mutation is significantly associated with the mutation status of many other genes, with 2,820 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM111B-associated genes across cancer lineages are ALG3, INPP5B, and FGGY. Each is linked with FAM111B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM111B-to-partner and partner-to-FAM111B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111B→partner) and Y-score (partner→FAM111B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ALG3 →	+5.247	+4.429	.005	.005	1	3
OVARY	INPP5B →	+4.977	+4.415	.007	.007	1	3
OVARY	FGGY →	+4.977	+4.415	.007	.007	1	3
OVARY	KDM2A →	+4.562	+5.217	<.001	<.001	1	3
OVARY	UPF1 →	+4.977	+4.415	.007	.007	1	3
OVARY	WAPL →	+4.977	+4.415	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,820 associations by consensus.

Exploration

FAM111B survival (RNA) · tumor vs normal (RNA) · all FAM111B data types