Across TCGA patient cohorts, FAM110D mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM110D-associated genes across cancer lineages are RNA5SP419, SMIM12P1, and RN7SL726P. Each is linked with FAM110D in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM110D-to-partner and partner-to-FAM110D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110D→partner) and Y-score (partner→FAM110D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+1.804	+4.077	<.001	.001	3	2
UCEC	SMIM12P1 →	+0.371	+3.813	.004	.002	3	1
UCEC	RN7SL726P →	+0.227	+3.488	.002	.008	3	1
UCEC	MIR7702 →	+0.629	+6.060	<.001	<.001	3	1
UCEC	RNA5SP411 →	+2.204	+3.393	<.001	.007	3	1
UCEC	MIR6763 →	+0.970	+3.663	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

FAM110D survival (RNA) · tumor vs normal (RNA) · all FAM110D data types