FAM110C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM110C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM110C-associated GO terms across cancer lineages are Establishment or maintenance of microtubule cytoskeleton polarity, Keratinocyte development, and Negative regulation of Arp2/3 complex-mediated actin nucleation. Each is linked with FAM110C in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM110C-to-partner and partner-to-FAM110C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110C→partner) and Y-score (partner→FAM110C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYEstablishment or maintenance of microtubule cytoskeleton polarity →-0.330-2.340<.001<.001310
URINARY_TRACTKeratinocyte development →-0.474-2.882<.001<.00139
STOMACHNegative regulation of Arp2/3 complex-mediated actin nucleation →+0.182+1.574<.001<.00139
URINARY_TRACTEstablishment of epithelial cell apical/basal polarity →-0.194-2.658.002<.00139
BREASTtRNA wobble uridine modification →-0.075-1.684.001<.001210
URINARY_TRACTResponse to indole-3-methanol →+0.200+2.175<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,845 associations by consensus.

Exploration