Across TCGA cell cohorts, FAM110C mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM110C-associated genes across cancer lineages are C1QC, CLEC4D, and ACSM6. Each is linked with FAM110C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM110C-to-partner and partner-to-FAM110C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110C→partner) and Y-score (partner→FAM110C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	C1QC →	+0.013	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	CLEC4D →	+0.006	+4.643	<.001	.008	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.169	<.001	.007	3	1
LARGE_INTESTINE	OR4F5 →	+0.029	+3.930	<.001	.003	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

FAM110C survival (RNA) · tumor vs normal (RNA) · all FAM110C data types