FAM110B

Across TCGA cell cohorts, FAM110B mutation is significantly associated with the RNA expression of many other genes, with 322 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM110B-associated genes across cancer lineages are AHSA1, MBL2, and TMEM244. Each is linked with FAM110B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM110B-to-partner and partner-to-FAM110B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AHSA1 grouped by FAM110B-low versus FAM110B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110B→partner) and Y-score (partner→FAM110B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AHSA1 →	+0.516	+3.064	<.001	.009	3	2
BLOOD_Leukemia	MBL2 →	+0.006	+4.684	<.001	<.001	3	1
BLOOD_Leukemia	TMEM244 →	+0.239	+3.966	<.001	.001	3	1
BLOOD_Leukemia	PNLIPRP3 →	+0.012	+3.966	<.001	.001	3	1
BLOOD_Leukemia	ACCSL →	+0.203	+3.242	<.001	.007	3	1
BLOOD_Leukemia	SLC5A8 →	+0.092	+4.201	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 322 associations by consensus.

AHSA1 by FAM110B expression — LARGE_INTESTINE

Explore this box plot interactively →