FAM110A

Across TCGA pan-cancer cohorts, FAM110A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM110A data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM110A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM110A expression acts as an unfavorable survival marker.

SKCM, BRCA, and KICH are the cancer types where FAM110A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.230	0.783	.002	30	view →
BRCA	OS	Median	All	0.088	0.924	<.001	24	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM110A–SKCM (OS)

Open the SKCM breakdown →