FAM110A

Across TCGA patient cohorts, FAM110A mutation is significantly associated with the RNA expression of many other genes, with 134 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM110A-associated genes across cancer lineages are RNU6-48P, HLA-P, and RNA5SP534. Each is linked with FAM110A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM110A-to-partner and partner-to-FAM110A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-48P grouped by FAM110A-low versus FAM110A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110A→partner) and Y-score (partner→FAM110A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-48P →	+0.766	+2.745	<.001	.009	3	2
UCEC	HLA-P →	+0.209	+3.653	.009	.005	3	2
UCEC	RNA5SP534 →	+0.393	+3.242	<.001	.007	3	1
UCEC	RNA5SP414 →	+0.874	+3.577	<.001	<.001	3	1
UCEC	MIR7702 →	+0.415	+5.253	<.001	.001	3	1
UCEC	MIR8055 →	+0.797	+3.912	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 134 associations by consensus.

RNU6-48P by FAM110A expression — UCEC

Explore this box plot interactively →