FAM110A

Across TCGA cell cohorts, FAM110A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,232 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAM110A-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Regulation of protein localization to endoplasmic reticulum, and Establishment or maintenance of epithelial cell apical/basal polarity. Each is linked with FAM110A in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM110A-to-partner and partner-to-FAM110A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by FAM110A-low versus FAM110A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM110A→partner) and Y-score (partner→FAM110A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of protein localization to endoplasmic reticulum →	+0.151	+1.237	<.001	<.001	3	16
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.158	+1.237	<.001	<.001	3	15
OESOPHAGUS	Establishment or maintenance of epithelial cell apical/basal polarity →	+0.156	+1.994	.001	<.001	3	12
KIDNEY	Positive regulation of plasma cell differentiation →	+0.164	+1.184	.001	.001	3	11
BONE	Regulation of protein localization to nucleus →	+0.085	+1.577	<.001	.007	3	11
URINARY_TRACT	Positive regulation of protein import into nucleus →	+0.143	+1.282	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by FAM110A expression — KIDNEY

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