FAM107A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM107A protein abundance is significantly associated with the RNA expression of many other genes, with 4,349 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM107A-associated genes across cancer lineages are NDRG4, PGAP4, and CALM1. Each is linked with FAM107A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM107A-to-partner and partner-to-FAM107A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM107A versus NDRG4 in LSCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM107A→partner) and Y-score (partner→FAM107A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCNDRG4 →-0.974-0.605.009.00132
OVPGAP4 →+1.399+1.402.002.00332
UCECCALM1 →-0.683-1.161<.001.00132
LSCCFAM72C →-0.603-0.587<.001.00632
UCECIL5 →+1.343+1.231.001.00132
GBMNAPB →+0.746+0.546<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,349 associations by consensus.

FAM107A vs NDRG4 — LSCC

Per-sample scatter of FAM107A vs NDRG4 in LSCC (Pearson r = -0.33).

Explore this scatter interactively →

Exploration