FAM107A

Across TCGA patient cohorts, FAM107A mutation is significantly associated with the RNA expression of many other genes, with 920 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM107A-associated genes across cancer lineages are RNU1-130P, RNU6-1233P, and DNM1P32. Each is linked with FAM107A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM107A-to-partner and partner-to-FAM107A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-130P grouped by FAM107A-low versus FAM107A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM107A→partner) and Y-score (partner→FAM107A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU1-130P →	+0.298	+7.930	<.001	.008	3	2
LUSC	RNU6-1233P →	+0.314	+4.606	<.001	.006	3	2
LUSC	DNM1P32 →	+0.054	+4.297	<.001	.009	3	2
LUSC	AQP7P3 →	+0.102	+4.393	<.001	.008	3	2
STAD	RN7SKP42 →	+0.215	+4.929	<.001	.002	3	2
STAD	RN7SL719P →	+0.143	+5.070	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 920 associations by consensus.

RNU1-130P by FAM107A expression — LUAD

Explore this box plot interactively →