FAM104A

Across TCGA patient cohorts, FAM104A protein abundance is significantly associated with the RNA expression of many other genes, with 4,978 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM104A-associated genes across cancer lineages are XBP1, OLFM2, and MLPH. Each is linked with FAM104A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM104A-to-partner and partner-to-FAM104A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM104A versus XBP1 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM104A→partner) and Y-score (partner→FAM104A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XBP1 →	+1.237	+0.395	.002	<.001	3	2
UCEC	OLFM2 →	-1.122	-0.601	.002	.002	2	3
UCEC	MLPH →	+1.633	+0.637	<.001	.001	3	2
BRCA	LURAP1L →	+1.223	+0.464	.002	.001	3	2
BRCA	TFF1 →	+3.716	+0.326	<.001	.001	3	2
BRCA	PLEKHD1 →	+1.013	+0.419	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,978 associations by consensus.

FAM104A vs XBP1 — BRCA

Explore this scatter interactively →