FAM102B

Across TCGA patient cohorts, FAM102B mutation is significantly associated with the RNA expression of many other genes, with 1,823 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM102B-associated genes across cancer lineages are PRAMEF27, HNRNPCL3, and OFD1P6Y. Each is linked with FAM102B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM102B-to-partner and partner-to-FAM102B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF27 grouped by FAM102B-low versus FAM102B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM102B→partner) and Y-score (partner→FAM102B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	PRAMEF27 →	+0.616	+4.174	<.001	.009	3	2
UCEC	HNRNPCL3 →	+0.035	+2.078	.001	.006	3	2
HNSC	OFD1P6Y →	+0.008	+5.241	.009	.007	3	2
LIHC	LINC02024 →	+0.037	+4.647	<.001	.007	3	2
UCEC	MIR1276 →	+0.395	+1.937	.004	.003	3	2
UCEC	SEPTIN7P7 →	+0.127	+2.685	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,823 associations by consensus.

PRAMEF27 by FAM102B expression — LIHC

Explore this box plot interactively →