FAIM2

Across TCGA cell cohorts, FAIM2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAIM2-associated genes across cancer lineages are UNCX, C10orf53, and OR10G7. Each is linked with FAIM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAIM2-to-partner and partner-to-FAIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNCX grouped by FAIM2-low versus FAIM2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAIM2→partner) and Y-score (partner→FAIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	UNCX →	+0.139	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	C10orf53 →	+0.018	+4.734	.004	.002	3	1
LUNG_NSCLC_LUAD	OR10G7 →	+0.012	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	SHOX →	+0.015	+4.947	.001	.001	3	1
LUNG_NSCLC_LUAD	LIPN →	+0.034	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	LCE1F →	+0.113	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

UNCX by FAIM2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →