FAIM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAIM RNA expression is significantly associated with the protein abundance of many other proteins, with 10,558 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAIM-associated proteins across cancer lineages are DBR1, MVP, and UBXN7. Each is linked with FAIM in more than 4 cancer types. Because this analysis shows association rather than direction, both FAIM-to-partner and partner-to-FAIM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAIM versus DBR1 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAIM→partner) and Y-score (partner→FAIM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDBR1 →+0.320+0.614<.001<.00135
GBMMVP →-0.569-0.306<.001<.00135
HNSCUBXN7 →+0.498+0.789<.001<.00134
UCECUSP13 →+0.360+0.532.006.00934
LSCCZNF148 →+0.282+0.543<.001<.00134
HNSCZNF326 →+0.387+0.611<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,558 associations by consensus.

FAIM vs DBR1 — LSCC

Per-sample scatter of FAIM vs DBR1 in LSCC (Pearson r = 0.62).

Explore this scatter interactively →

Exploration