FAIM

Across TCGA patient cohorts, FAIM protein abundance is significantly associated with the RNA expression of many other genes, with 4,044 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAIM-associated genes across cancer lineages are CEP70, DBR1, and GMPS. Each is linked with FAIM in more than 4 cancer types. Because this analysis shows association rather than direction, both FAIM-to-partner and partner-to-FAIM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAIM versus CEP70 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAIM→partner) and Y-score (partner→FAIM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEP70 →	+1.041	+0.349	<.001	<.001	3	5
HNSC	DBR1 →	+0.598	+0.342	<.001	<.001	3	3
HNSC	GMPS →	+0.507	+0.256	.001	.002	3	3
LSCC	ATR →	+0.486	+0.374	<.001	<.001	3	3
LSCC	MRPS22 →	+0.619	+0.397	<.001	<.001	3	3
LSCC	PXYLP1 →	+0.611	+0.326	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,044 associations by consensus.

FAIM vs CEP70 — HNSC

Explore this scatter interactively →