FAIM

Across TCGA cell cohorts, FAIM RNA expression is significantly associated with the go_rna of many other GO terms, with 3,881 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAIM-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Regulation of metaphase/anaphase transition of cell cycle, and Regulation of mitotic spindle checkpoint. Each is linked with FAIM in more than 10 cancer types. Because this analysis shows association rather than direction, both FAIM-to-partner and partner-to-FAIM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by FAIM-low versus FAIM-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAIM→partner) and Y-score (partner→FAIM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.167	+1.193	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.102	+1.315	.003	.001	3	9
BLOOD_Leukemia	Regulation of mitotic spindle checkpoint →	+0.103	+2.357	<.001	<.001	3	9
PANCREAS	Regulation of chromosome separation →	+0.103	+0.804	.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.100	+1.197	.004	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.096	+1.006	.005	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,881 associations by consensus.

Establishment of mitotic sister chromatid cohesion by FAIM expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →