FAHD2B

Across TCGA pan-cancer cohorts, FAHD2B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FAHD2B data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAHD2B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FAHD2B expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where FAHD2B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.408	1.000	.007	16	view →
CCRCC	DFS	Tertile	All	0.649	0.886	.016	9	view →
HNSC	DFS	Median	II,III,IV	0.878	0.986	.012	7	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
LSCC	OS	Median	All	1.000	0.953	.024	2	view →
PDAC	OS	Median	II,III,IV	0.618	1.000	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FAHD2B–UCEC (OS)

Open the UCEC breakdown →