FAHD2B

Across TCGA patient cohorts, FAHD2B mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAHD2B-associated genes across cancer lineages are eEF2, STAT5a, and Claudin-7. Each is linked with FAHD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD2B-to-partner and partner-to-FAHD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by FAHD2B-low versus FAHD2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD2B→partner) and Y-score (partner→FAHD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.410	+3.000	.047	.037	3	1
UCEC	STAT5a →	+0.477	+3.000	.039	.037	3	1
UCEC	Claudin-7 →	-0.598	-3.000	.040	.037	3	1
UCEC	Di-Ras3 →	-0.190	-3.000	.027	.037	3	1
UCEC	14-3-3_beta →	-0.165	-2.986	.004	.037	2	1
UCEC	MEK1 →	+0.578	+3.000	.006	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

eEF2 by FAHD2B expression — UCEC

Explore this box plot interactively →