FAHD2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAHD2A mutation is significantly associated with the RNA expression of many other genes, with 1,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAHD2A-associated genes across cancer lineages are LINC02133, RN7SL504P, and COX5AP2. Each is linked with FAHD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD2A-to-partner and partner-to-FAHD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02133 grouped by FAHD2A-low versus FAHD2A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD2A→partner) and Y-score (partner→FAHD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC02133 →+0.093+3.882<.001.00832
SKCMRN7SL504P →+0.083+5.485<.001.00132
UCECCOX5AP2 →+0.397+1.819.001.00832
BRCAOR7E93P →+0.195+4.575<.001.00931
BRCALINC01739 →+0.117+5.112<.001.00431
BRCABMS1P19 →+0.205+4.941<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,438 associations by consensus.

LINC02133 by FAHD2A expression — SKCM

Box plot of LINC02133 in FAHD2A-low vs FAHD2A-high samples in SKCM.

Explore this box plot interactively →

Exploration