FAHD2A

Across TCGA patient cohorts, FAHD2A mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAHD2A-associated genes across cancer lineages are BRD4, 14-3-3_beta, and eEF2. Each is linked with FAHD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD2A-to-partner and partner-to-FAHD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRD4 grouped by FAHD2A-low versus FAHD2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD2A→partner) and Y-score (partner→FAHD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BRD4 →	+0.260	+3.010	.026	.019	3	2
UCEC	14-3-3_beta →	-0.110	-3.143	.010	.018	3	1
UCEC	eEF2 →	+0.442	+3.321	.003	.010	3	1
UCEC	EGFR_pY1068 →	-0.308	-2.222	.003	.011	3	1
UCEC	eIF4G →	+0.298	+2.222	.023	.011	3	1
UCEC	A-Raf_pS299 →	-0.176	-2.222	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

BRD4 by FAHD2A expression — UCEC

Explore this box plot interactively →