FAHD2A

Across TCGA cell cohorts, FAHD2A mutation is significantly associated with the drug of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAHD2A-associated genes across cancer lineages are kb NB 142-70, CD532, and Oxaliplatin. Each is linked with FAHD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD2A-to-partner and partner-to-FAHD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, kb NB 142-70 grouped by FAHD2A-low versus FAHD2A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD2A→partner) and Y-score (partner→FAHD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	kb NB 142-70 →	+0.517	+2.652	.028	.045	3	1
LARGE_INTESTINE	CD532 →	+0.415	+2.652	.039	.045	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.545	+2.649	.040	.046	2	1
LARGE_INTESTINE	Quizartinib →	+0.426	+2.652	.007	.045	2	1
LARGE_INTESTINE	AZD1208 →	+0.413	+2.649	.016	.046	1	1
LARGE_INTESTINE	150412 →	+0.374	+2.777	.026	.038	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

kb NB 142-70 by FAHD2A expression — LARGE_INTESTINE

Explore this box plot interactively →