FAHD1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FAHD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAHD1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FAHD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FAHD1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, LUAD, and UCEC are the cancer types where FAHD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSMedianAll0.6820.472.01020view →
LUADDFSMedianII,III,IV0.7210.937.0079view →
UCECDFSMedianAll0.9361.000.0236view →
LSCCDFSMedianII,III,IV0.8830.662.0186view →
CCRCCDFSMedianAll0.6560.840.0421view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAHD1–PDAC (OS)

Kaplan–Meier survival curve for FAHD1 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration