FAHD1

Across TCGA patient cohorts, FAHD1 mutation is significantly associated with the RNA expression of many other genes, with 779 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAHD1-associated genes across cancer lineages are RNA5SP499, DNAJB5P1, and TXN2. Each is linked with FAHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD1-to-partner and partner-to-FAHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP499 grouped by FAHD1-low versus FAHD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD1→partner) and Y-score (partner→FAHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP499 →	+0.123	+4.253	<.001	.004	3	2
UCEC	DNAJB5P1 →	+0.184	+2.010	<.001	.005	3	2
UCEC	TXN2 →	+0.370	+2.903	.005	.001	3	1
UCEC	SLC25A17 →	+0.381	+3.201	.008	.009	3	1
UCEC	PHF5A →	+0.652	+3.906	<.001	<.001	3	1
UCEC	POLE2 →	+0.676	+3.480	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 779 associations by consensus.

RNA5SP499 by FAHD1 expression — UCEC

Explore this box plot interactively →