FAH

Across TCGA pan-cancer cohorts, FAH mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAH data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAH mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FAH expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

HNSC, COAD, and CCRCC are the cancer types where FAH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.935	1.000	.015	8	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
CCRCC	OS	Tertile	III,IV	0.977	0.104	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAH–HNSC (OS)

Open the HNSC breakdown →