FAF1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,693 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAF1-associated GO terms across cancer lineages are Regulation of mitotic metaphase/anaphase transition, Regulation of chromosome segregation, and Negative regulation of chromosome segregation. Each is linked with FAF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FAF1-to-partner and partner-to-FAF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAF1→partner) and Y-score (partner→FAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTRegulation of mitotic metaphase/anaphase transition →+0.109+0.844.003<.001312
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome segregation →+0.112+0.741.003.002312
PANCREASNegative regulation of chromosome segregation →+0.123+0.643.001.002312
PANCREASCentromeric sister chromatid cohesion →+0.125+0.778<.001<.001312
UPPER_AERODIGESTIVE_TRACTProtein localization to chromosome, centromeric region →+0.135+0.836.005.001312
BLOOD_LymphomaNegative regulation of metaphase/anaphase transition of cell cycle →+0.091+0.793<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,693 associations by consensus.

Exploration