Across TCGA cell cohorts, FAF1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAF1-associated genes across cancer lineages are CNTN6, ANKRD30BL, and HPGDS. Each is linked with FAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAF1-to-partner and partner-to-FAF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAF1→partner) and Y-score (partner→FAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CNTN6 →	+0.673	+4.054	<.001	.004	3	1
LUNG_NSCLC_LUAD	ANKRD30BL →	+0.038	+4.149	<.001	<.001	3	1
LUNG_NSCLC_LUAD	HPGDS →	+0.047	+3.700	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR56A4 →	+0.144	+3.362	<.001	.007	3	1
LUNG_NSCLC_LUAD	KRTAP20-2 →	+0.228	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP19-5 →	+0.186	+3.628	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

FAF1 survival (RNA) · tumor vs normal (RNA) · all FAF1 data types