FADS6

Across TCGA patient cohorts, FADS6 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FADS6-associated genes across cancer lineages are CD8+ Tcm, MPP, and Neurons. Each is linked with FADS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FADS6-to-partner and partner-to-FADS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by FADS6-low versus FADS6-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS6→partner) and Y-score (partner→FADS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD8+ Tcm →	+0.055	+2.705	.011	.029	3	2
LUAD	MPP →	+0.013	+3.410	.011	.025	3	1
SKCM	Neurons →	-0.025	-2.888	.019	.036	3	1
GBM	CD4+ naive T-cells →	+0.007	+5.614	.007	.039	3	1
UCEC	Class-switched memory B-cells →	-0.056	-2.459	.042	.020	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ Tcm by FADS6 expression — LUAD

Explore this box plot interactively →