FADS6

Across TCGA cell cohorts, FADS6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FADS6-associated genes across cancer lineages are KRTAP17-1 and MAGEB4. Each is linked with FADS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FADS6-to-partner and partner-to-FADS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP17-1 grouped by FADS6-low versus FADS6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS6→partner) and Y-score (partner→FADS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRTAP17-1 →	+0.025	+4.977	<.001	.007	3	1
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP17-1 by FADS6 expression — SKIN

Explore this box plot interactively →