FADS2

Across TCGA patient cohorts, FADS2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FADS2-associated genes across cancer lineages are FADS1, DHCR7, and GPR137C. Each is linked with FADS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FADS2-to-partner and partner-to-FADS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FADS2 versus FADS1 in HNSC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS2→partner) and Y-score (partner→FADS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FADS1 →	+1.005	+0.817	<.001	<.001	3	7
HNSC	DHCR7 →	+1.377	+0.612	<.001	<.001	3	6
UCEC	GPR137C →	+0.985	+0.870	<.001	<.001	3	6
LSCC	GPT2 →	+0.814	+0.538	<.001	.007	3	5
GBM	RCOR2 →	+1.073	+0.461	<.001	<.001	3	5
LSCC	MEX3A →	+1.261	+0.742	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,026 associations by consensus.

FADS2 vs FADS1 — HNSC

Explore this scatter interactively →