FADS2

Across TCGA cell cohorts, FADS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,976 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FADS2-associated GO terms across cancer lineages are Positive regulation of response to oxidative stress, Alpha-linolenic acid metabolic process, and Linoleic acid metabolic process. Each is linked with FADS2 in more than 18 cancer types. Because this analysis shows association rather than direction, both FADS2-to-partner and partner-to-FADS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of response to oxidative stress grouped by FADS2-low versus FADS2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS2→partner) and Y-score (partner→FADS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of response to oxidative stress →	+0.301	+4.005	<.001	<.001	3	19
BLOOD_Myeloma	Alpha-linolenic acid metabolic process →	+0.232	+3.424	<.001	<.001	3	18
OESOPHAGUS	Linoleic acid metabolic process →	+0.337	+3.055	<.001	<.001	3	18
LUNG_NSCLC_LUAD	Unsaturated fatty acid biosynthetic process →	+0.142	+2.255	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Sterol biosynthetic process →	+0.171	+2.957	<.001	.009	3	15
BONE	Cholesterol biosynthetic process via lathosterol →	+0.203	+1.956	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,976 associations by consensus.

Positive regulation of response to oxidative stress by FADS2 expression — BLOOD_Myeloma

Explore this box plot interactively →