FADS2

Across TCGA cell cohorts, FADS2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FADS2-associated genes across cancer lineages are BTBD16, TACR3, and TNP2. Each is linked with FADS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FADS2-to-partner and partner-to-FADS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD16 grouped by FADS2-low versus FADS2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS2→partner) and Y-score (partner→FADS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BTBD16 →	+0.086	+3.959	<.001	.005	3	1
BLOOD_Leukemia	TACR3 →	+0.024	+4.060	<.001	.003	3	1
BLOOD_Leukemia	TNP2 →	+0.045	+4.037	.001	.004	3	1
BLOOD_Leukemia	UCN3 →	+0.024	+3.855	<.001	.007	3	1
BLOOD_Leukemia	NCMAP →	+0.020	+4.275	.005	.006	3	1
BLOOD_Leukemia	EBF2 →	+0.232	+3.999	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

BTBD16 by FADS2 expression — BLOOD_Leukemia

Explore this box plot interactively →