FADS1

Across TCGA cell cohorts, FADS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,771 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FADS1-associated GO terms across cancer lineages are Linoleic acid metabolic process, Alpha-linolenic acid metabolic process, and Positive regulation of response to oxidative stress. Each is linked with FADS1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FADS1-to-partner and partner-to-FADS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Linoleic acid metabolic process grouped by FADS1-low versus FADS1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS1→partner) and Y-score (partner→FADS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Linoleic acid metabolic process →	+0.309	+1.391	<.001	<.001	3	17
OESOPHAGUS	Alpha-linolenic acid metabolic process →	+0.233	+1.776	<.001	.002	3	15
OESOPHAGUS	Positive regulation of response to oxidative stress →	+0.293	+2.706	<.001	<.001	3	13
OESOPHAGUS	RNA localization →	+0.114	+2.442	<.001	<.001	3	13
BONE	Protein-DNA complex assembly →	+0.068	+1.292	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Unsaturated fatty acid biosynthetic process →	+0.198	+1.250	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,771 associations by consensus.

Linoleic acid metabolic process by FADS1 expression — KIDNEY

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