FADS1

Across TCGA cell cohorts, FADS1 mutation is significantly associated with the mutation status of many other genes, with 2,081 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FADS1-associated genes across cancer lineages are COL9A2, SREBF1, and SLC18A1. Each is linked with FADS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FADS1-to-partner and partner-to-FADS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL9A2 grouped by FADS1-low versus FADS1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS1→partner) and Y-score (partner→FADS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	COL9A2 →	+4.309	+4.560	.007	.007	1	3
LARGE_INTESTINE	SREBF1 →	+2.422	+4.050	.004	.004	1	3
LARGE_INTESTINE	SLC18A1 →	+3.007	+3.584	.008	.008	1	2
LARGE_INTESTINE	CAMKK1 →	+3.329	+3.799	.005	.005	1	2
BLOOD_Leukemia	SLC25A13 →	+6.479	+6.479	<.001	<.001	1	2
BLOOD_Leukemia	FOXC1 →	+4.309	+4.560	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,081 associations by consensus.

COL9A2 by FADS1 expression — BLOOD_Leukemia

Explore this box plot interactively →