FADD

Across TCGA patient cohorts, FADD protein abundance is significantly associated with the RNA expression of many other genes, with 4,273 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FADD-associated genes across cancer lineages are CTTN, PPFIA1, and LTO1. Each is linked with FADD in more than 5 cancer types. Because this analysis shows association rather than direction, both FADD-to-partner and partner-to-FADD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FADD versus CTTN in HNSC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADD→partner) and Y-score (partner→FADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTTN →	+1.291	+0.747	<.001	<.001	3	6
HNSC	PPFIA1 →	+1.498	+0.845	<.001	<.001	3	4
HNSC	LTO1 →	+1.407	+0.775	<.001	<.001	3	4
HNSC	ANO1 →	+1.672	+0.695	<.001	<.001	3	3
UCEC	CDK2AP2 →	+0.626	+0.241	.002	.002	3	3
HNSC	MRPL21 →	+1.221	+0.692	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,273 associations by consensus.

FADD vs CTTN — HNSC

Explore this scatter interactively →