FADD

Across TCGA cell cohorts, FADD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,858 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FADD-associated GO terms across cancer lineages are Regulation of CD8-positive, alpha-beta T cell extravasation, Death-inducing signaling complex assembly, and CAAX-box protein processing. Each is linked with FADD in more than 15 cancer types. Because this analysis shows association rather than direction, both FADD-to-partner and partner-to-FADD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of CD8-positive, alpha-beta T cell extravasation grouped by FADD-low versus FADD-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FADD→partner) and Y-score (partner→FADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of CD8-positive, alpha-beta T cell extravasation →	+0.819	+1.281	.001	<.001	3	16
STOMACH	Death-inducing signaling complex assembly →	+0.176	+0.790	<.001	<.001	3	12
OESOPHAGUS	CAAX-box protein processing →	+0.133	+1.364	.003	.007	3	12
PANCREAS	Response to dehydroepiandrosterone →	+0.150	+0.737	.001	<.001	3	11
OESOPHAGUS	Spliceosomal tri-snRNP complex assembly →	+0.117	+2.014	.006	.001	3	11
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.146	+0.741	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,858 associations by consensus.

Regulation of CD8-positive, alpha-beta T cell extravasation by FADD expression — LUNG_SCLC

Explore this box plot interactively →