FABP5P3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FABP5P3 mutation is significantly associated with the RNA expression of many other genes, with 1,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP5P3-associated genes across cancer lineages are DEFB127, PPP2R2DP1, and GATD1. Each is linked with FABP5P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP5P3-to-partner and partner-to-FABP5P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB127 grouped by FABP5P3-low versus FABP5P3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP5P3→partner) and Y-score (partner→FABP5P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCDEFB127 →+0.119+4.505<.001.00932
HNSCPPP2R2DP1 →+0.161+4.425<.001.00632
UCECGATD1 →+0.462+3.223.003.00932
UCECRNA5SP412 →+0.495+2.382.004.00332
UCECCIDECP1 →+0.516+3.860<.001<.00132
UCECRNU6-1067P →+0.269+2.453.002.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,439 associations by consensus.

DEFB127 by FABP5P3 expression — HNSC

Box plot of DEFB127 in FABP5P3-low vs FABP5P3-high samples in HNSC.

Explore this box plot interactively →

Exploration