FABP5P3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FABP5P3 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP5P3-associated genes across cancer lineages are eIF4G, MEK1, and Notch1. Each is linked with FABP5P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP5P3-to-partner and partner-to-FABP5P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by FABP5P3-low versus FABP5P3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP5P3→partner) and Y-score (partner→FABP5P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeIF4G →+0.384+3.169.018.01931
UCECMEK1 →+0.475+3.321.013.01031
UCECNotch1 →+0.286+3.321<.001.01031
UCECRab25 →-0.520-3.000.002.03631
UCECC-Raf →+0.255+3.169<.001.01922
UCECFoxM1 →+0.376+2.817.005.03621
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

eIF4G by FABP5P3 expression — UCEC

Box plot of eIF4G in FABP5P3-low vs FABP5P3-high samples in UCEC.

Explore this box plot interactively →

Exploration