FABP2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FABP2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FABP2-associated genes across cancer lineages are MEP, Platelets, and Epithelial cells. Each is linked with FABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP2-to-partner and partner-to-FABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by FABP2-low versus FABP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP2→partner) and Y-score (partner→FABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEP →+0.040+2.839.006.03532
SKCMPlatelets →+0.022+2.032<.001.01631
UCECEpithelial cells →-0.096-2.989.011.03531
SKCMMast cells →-0.020-2.905.025.03721
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MEP by FABP2 expression — UCEC

Box plot of MEP in FABP2-low vs FABP2-high samples in UCEC.

Explore this box plot interactively →

Exploration