FAAP24

Across TCGA patient cohorts, FAAP24 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAAP24-associated genes across cancer lineages are Caspase-7-cleavedD198, MEK1, and Caspase-8. Each is linked with FAAP24 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAAP24-to-partner and partner-to-FAAP24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by FAAP24-low versus FAAP24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAAP24→partner) and Y-score (partner→FAAP24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.990	+3.019	<.001	.019	3	2
UCEC	MEK1 →	+0.384	+3.000	.029	.036	3	1
UCEC	Caspase-8 →	-0.305	-3.584	.012	.002	3	1
UCEC	Di-Ras3 →	-0.167	-3.156	.019	.018	3	1
UCEC	ATM →	-0.595	-2.459	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Caspase-7-cleavedD198 by FAAP24 expression — UCEC

Explore this box plot interactively →